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The Cardiovascular CME podcast is a free educational offering from Mayo Clinic, featuring content geared towards physicians, physician assistants, and nurse practitioners who are interested in exploring a multitude of cardiology-related topics.
Tune in and subscribe to explore today’s most pressing cardiology topics with your colleagues at Mayo Clinic and gain valuable insights that can be directly applied to your practice.
No CME credit offered for podcast episodes at this time.
Episodes
4 days ago
4 days ago
Clopidogrel Monotherapy in Chronic Coronary Artery Disease
Guest: Keri Zieminski, APRN, C.N.P., D.N.P.
Host: Sharonne Hayes, M.D.
This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of clopidogrel monotherapy in patients with chronic CAD that are not on anticoagulation. Discussion will include why there has been a shift towards redefining antiplatelet medical therapy for this patient population, brief overview of recent trials, and how to manage a patient on clopidogrel monotherapy that needs to undergo noncardiac surgery.
Topics Discussed:
- Why has there been a shift towards redefining antiplatelet medical therapy in patients with chronic CAD? What's changed?
- Recently published trials that highlight clopidogrel monotherapy.
- What is your process for managing a patient on clopidogrel monotherapy that needs to go for noncardiac surgery?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Jan 06, 2026
Tuesday Jan 06, 2026
Global Practices in Cardiac Imaging for Cardiac Sarcoidosis
Guest: Tahir Kafil, M.D.
Host: Sharonne Hayes, M.D.
Cardiac imaging is a cornerstone in the diagnostic work-up and management of cardiac sarcoidosis. However, indications and use of advanced cardiac imaging vary from institution to institution, and even between providers at the same institution. We conducted an international Delphi consensus study of 89 global experts in cardiac sarcoidosis to evaluate real-world clinical practices and use of advanced cardiac imaging. We developed consensus for use of advanced cardiac imaging in cardiac sarcoidosis. Areas lacking consensus were noted as priority areas for research.
Topics Discussed:
- From a big picture perspective, how is cardiac sarcoidosis generally diagnosed?
- What exactly is the Delphi methodology your team used to build consensus?
- The suggested algorithm for imaging in suspected cardiac sarcoidosis uses pretest probability, how was that defined?
- Was cardiac MRI superior to PET in your study? Does one have to be first?
- How do experts decide how often to do follow up PET imaging in established cardiac sarcoidosis?
- What were areas of priority research that were identified?
The research study cited by Dr. Kafil was published on June 2, 2025. Click the following link to view the paper:
https://www.jacc.org/doi/full/10.1016/j.jcmg.2025.02.010
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Dec 30, 2025
Tuesday Dec 30, 2025
Anticoagulation Monotherapy in Patients with Chronic Coronary Artery Disease and Atrial Fibrillation
Guest: Keri Zieminski, APRN, C.N.P., D.N.P.
Host: Sharonne Hayes, M.D.
This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of anticoagulation monotherapy in patients with chronic CAD and atrial fibrillation. Discussion will include a brief overview of recently published trials that highlight the use of anticoagulation monotherapy in chronic CAD with atrial fibrillation, and how to manage a patient on anticoagulation monotherapy that needs to undergo noncardiac surgery.
Topics Discussed:
- Why has there been a shift towards redefining antithrombotic medical therapy in patients with chronic CAD with atrial fibrillation? What's changed?
- Recently published trials that highlight the use of anticoagulation monotherapy in the chronic CAD + AF population.
- What is your process for managing a patient on anticoagulation monotherapy that needs to go for noncardiac surgery?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Dec 23, 2025
Tuesday Dec 23, 2025
Updated Guidelines for Perioperative Cardiovascular Management for Noncardiac Surgery
Guest: Michael Cullen, M.D.
Host: Kyle Klarich, M.D.
This episode of Mayo Clinic’s “Interviews With the Experts” reviews the assessment of patients with known or suspected cardiovascular disease undergoing noncardiac surgery. Dr. Michael Cullen discusses recommendations from 2024 ACC/AHA perioperative guidelines regarding medication management before and after noncardiac surgery, including recommendations for antiplatelet therapy and bridging anticoagulation. Finally, he highlights new recommendations in the recent 2024 ACC/AHA perioperative guidelines and compare these guidelines to the 2022 European Society of Cardiology perioperative guidelines.
Topics Discussed:
- How should clinicians approach the assessment of a patient prior to noncardiac surgery?
- How should physicians and APPs manage cardiac medications around the time of noncardiac surgery?
- What are some of the new recommendations in the 2024 ACC/AHA guidelines for perioperative management prior to noncardiac surgery?
- How do the 2024 ACC/AHA perioperative guidelines differ from the 2022 ESC noncardiac surgery guidelines?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Dec 16, 2025
Tuesday Dec 16, 2025
Obesity, Hypertension, and Risk Factors in Terms of Prevention and Decreasing the Risk of HfpEF
Guest: Affan Irfan, M.D., Ph.D.
Host: Stephen L. Kopecky, M.D.
HFpEF is a type of heart failure where the heart pumps normally but becomes stiff. This leads to fatigue, shortness of breath, and fluid retention. It is closely linked to obesity, hypertension, and metabolic disorders, with cases rising as these conditions become more common.
Topics Discussed:
- What is HFpEF and its risk factors?
- How common are obesity and hypertension, and how often do they lead to HFpEF?
- How do you diagnose HFpEF?
- How effective are weight loss, diet, and exercise in preventing HFpEF?
- What medical and public health strategies help reduce these risk factors and HFpEF cases?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Dec 09, 2025
Tuesday Dec 09, 2025
Aortic Regurgitation: Beyond the Valve
Guest: Vidhu Anand, M.B.B.S.
Host: Kyle Klarich, M.D.
In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Klarich and Dr. Anand discuss evolving approaches to assessing left ventricular remodeling in chronic aortic regurgitation. Dr. Vidhu Anand discusses research showing that LV volumes, global longitudinal strain, and myocardial fibrosis can detect dysfunction earlier than traditional guideline thresholds. Listeners can expect to better understand the role of multimodality imaging, extra valvular involvement, and practical steps echocardiographers can take to optimize AR assessment.
Topics Discussed:
- What imaging markers help detect early myocardial dysfunction in AR, and how do they assist in risk stratification?
- Guidelines traditionally focus on LV dimensions and ejection fraction for surgical decision-making in AR. Is there any data that guidelines may not be capturing patients at the optimal time?
- Is there a role of multimodality imaging in AR?
- What practical steps can a sonographer or echocardiographer today to bring their AR assessment closer to what your research suggests is optimal?
Please reference Dr. Anand's research article(s) here:
https://pubmed.ncbi.nlm.nih.gov/39545891/
https://pubmed.ncbi.nlm.nih.gov/33253815/
https://pubmed.ncbi.nlm.nih.gov/39218370/
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Dec 02, 2025
Tuesday Dec 02, 2025
Presentation, Evaluation, and Management of Premature Ventricular Contractions
Guest: Alan M. Sugrue, M.B., B.Ch., B.A.O.
Host: Anthony H. Kashou, M.D.
In this episode, Dr. Anthony Kashou and Dr. Alan Sugrue cover a practical, evidence-based approach to premature ventricular contractions (PVCs), from incidental findings to high-burden, high-risk presentations. Listeners will gain tools to differentiate benign from pathologic PVCs, understand when to monitor versus refer, and recognize the role of catheter ablation in improving outcomes.
Topics Discussed:
- PVCs show up on Holters and ECGs all the time — how do you decide when they matter?
- How often do PVCs cause cardiomyopathy, and when should we act?
- When should we consider ablation even if the patient is asymptomatic?
- What’s the biggest misconception about PVC ablation today?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Nov 25, 2025
Tuesday Nov 25, 2025
Tricuspid Regurgitation: New Insights and Implications for Clinical Practice
Guest: Vidhu Anand, M.B.B.S.
Host: Kyle Klarich, M.D.
This episode of Mayo Clinic’s “Interviews With the Experts,” explores new insights into tricuspid regurgitation and its implications for clinical practice. Dr. Vidhu Anand discusses the dynamic nature of TR, its impact on prognosis, and the importance of close monitoring even when the condition appears to improve. The conversation highlights evolving guideline considerations, patient risk stratification, and how AI and machine learning may soon support earlier, more personalized interventions. Listeners will gain practical takeaways on when to escalate care and how to optimize long-term outcomes for TR patients.
Topics Discussed:
- How has our understanding of the natural history of tricuspid regurgitation changed, and what does this mean for the way we monitor and counsel patients?
- What are the current indications for intervention in isolated TR?
- How is TR currently classified? Are there any novel classifications based on patient’s risk profile, since comorbidities play an important role in TR?
- Review of Mayo Clinic study using AI/machine learning and outcomes in TR.
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Nov 18, 2025
Tuesday Nov 18, 2025
Cardiovascular Diet Myths
Guest: Stephen Kopecky, M.D.
Host: Sharonne Hayes, M.D.
Since 2018, Trans-Fats are prohibited from being a food additive in the US. In this episode of “Interviews With the Experts,” Dr. Stephen Kopecky discussed how trans fats are still in our food, just not as much as pre-2018, and the main sources of trans fat are ultra-processed foods. Listeners will learn what foods scan raise your blood cholesterol (LDL-C) levels, increase heart attack risk, accelerate the aging process, and slow the aging process.
Topics Discussed:
- Are some trans-fats still sneaking into our food?
- If a person eats food high in cholesterol, can blood levels of cholesterol (LDL-C) go up?
- Which artificial sweeteners increase CV risk?
- Can diet actually speed up or slow down the aging process?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
Tuesday Nov 11, 2025
Tuesday Nov 11, 2025
Evolving Treatment Landscape in Transthyretin Cardiac Amyloidosis
Guest: Rosalyn Adigun, M.D., Pharm.D.
Host: S. Allen Luis, M.B.B.S., Ph.D.
In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Allen Luis interviews Dr. Rosalyn Adigun on transthyretin cardiac amyloidosis. Listeners will come away with a detailed overview of the evolution of treatment options for patient diagnosed with transthyretin amyloid cardiomyopathy, highlighting historical perspectives, early registration studies, current treatment options, and an outlook on future directions in the management of transthyretin cardiac amyloidosis.
Topics Discussed:
- Overview of the historical perspectives on the diagnosis and management of transthyretin amyloidosis.
- Current treatment options available for transthyretin amyloid cardiomyopathy, and factors that should guide a clinician's decision regarding the choice of therapy.
- Treatment options in the coming years.
- Ongoing research initiatives in the management of cardiac amyloidosis.
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.