Mayo Clinic Cardiovascular CME

Dietary Guidelines for Americans: What Changed, What Didn’t, and Why it Matters

Dietary Guidelines of America: What Changed, What Didn’t, and Why it Matters

 

Guest: Dariush Mozaffarian, M.D., Dr.P.H.

Host: Kyla Lara-Breitinger, M.D., M.H.S.

 

The release of the new Dietary Guidelines for Americans has sparked important conversations across medicine, public health, and clinical practice. In this three-episode Interview with the Experts mini-series, Mayo Clinic preventive cardiologist Dr. Kyla Lara-Breitinger brings clarity to what the guidelines mean for patients and clinicians alike—cutting through headlines, controversy, and confusion with evidence-based insights from national and Mayo Clinic experts. Together, we explore what’s new, what remains unchanged, where debate persists, and how these guidelines translate into real-world cardiometabolic care, with a strong emphasis on practical, patient-centered nutrition advice.

 

Topics Discussed:

• Why does the new DGA matter for cardiology?
• What’s new vs. recycled?
• Core controversies
• Clinical takeaways

 

Referenced article:

Mozaffarian D. The 2025-2030 Dietary Guidelines for Americans. JAMA. Published online January 14, 2026. doi:10.1001/jama.2026.0283 The 2025-2030 Dietary Guidelines for Americans | Lifestyle Behaviors | JAMA | JAMA Network 

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

 

Recorded on: 27-January-2026

Conduction System Pacing

Conduction System Pacing

 

Guest: Nicholas Tan, M.D., M.S.

Host: Anthony Kashou, M.D.

 

In this episode of the “ECG Making Waves” segment of Mayo Clinic’s cardiovascular podcast series “Interviews with the Experts,” Dr. Nicholas Tan joins us to discuss conduction system pacing. The listener will hear about the basics and rationale of conduction system pacing, as well as clinical scenarios where it should be considered.

 

Topics Discussed:

• How does conduction system pacing (or CSP) differ from conventional means of pacing?
• In broad strokes, how is CSP performed?
• In what situations would you consider doing CSP?
• Are there any risks or uncertainties regarding CSP?

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

 

Recorded 09-December-2025

AI Detection of Cardiac Amyloidosis

AI Detection of Cardiac Amyloidosis

 

Guest: Patricia Pellikka, M.D.

Host: Malcolm Bell, M.D.

 

Dr. Patricia Pellikka dives into the AI model she helped build. Working with an AI echo company, Ultromics Ltd., her team built an AI echo model to detect cardiac amyloidosis. The model works from an apical 4 chamber videoclip and was approved by the FDA via the breakthrough pathway. They have validated it internationally in a population with 22% prevalence of cardiac amyloidosis and it had a sensitivity of 85%, specificity 93%, PPV 78%, NPV 96%, and AUC 0.93.  The performance of the model was consistent across cardiac amyloid types; among AL, wild type ATTR, and hereditary ATTR, the sensitivity was 84%, 85%, and 86%, respectively.  The performance of the model was also superior to previously validated scores which use clinical and echocardiographic variables for detecting cardiac amyloidosis. The results of the study were published online in the European Heart Journal in July.

 

Topics Discussed:

• You have built an AI echo model to detect cardiac amyloidosis.  How did you get into this?
• Tell us about the model that you built. How did you validate it?
• How does the model compare with other screening methods for detecting cardiac amyloidosis?
• What are the next steps for your research?

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

Clopidogrel Monotherapy in Chronic Coronary Artery Disease

Clopidogrel Monotherapy in Chronic Coronary Artery Disease

 

Guest: Keri Zieminski, APRN, C.N.P., D.N.P.

Host: Sharonne Hayes, M.D.

 

This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of clopidogrel monotherapy in patients with chronic CAD that are not on anticoagulation. Discussion will include why there has been a shift towards redefining antiplatelet medical therapy for this patient population, brief overview of recent trials, and how to manage a patient on clopidogrel monotherapy that needs to undergo noncardiac surgery.

 

Topics Discussed:

• Why has there been a shift towards redefining antiplatelet medical therapy in patients with chronic CAD? What's changed?
• Recently published trials that highlight clopidogrel monotherapy.
• What is your process for managing a patient on clopidogrel monotherapy that needs to go for noncardiac surgery?

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

Global Practices in Cardiac Imaging for Cardiac Sarcoidosis

Global Practices in Cardiac Imaging for Cardiac Sarcoidosis

 

Guest: Tahir Kafil, M.D.

Host: Sharonne Hayes, M.D.

 

Cardiac imaging is a cornerstone in the diagnostic work-up and management of cardiac sarcoidosis. However, indications and use of advanced cardiac imaging vary from institution to institution, and even between providers at the same institution. We conducted an international Delphi consensus study of 89 global experts in cardiac sarcoidosis to evaluate real-world clinical practices and use of advanced cardiac imaging. We developed consensus for use of advanced cardiac imaging in cardiac sarcoidosis. Areas lacking consensus were noted as priority areas for research.

 

Topics Discussed:

• From a big picture perspective, how is cardiac sarcoidosis generally diagnosed?
• What exactly is the Delphi methodology your team used to build consensus? 
• The suggested algorithm for imaging in suspected cardiac sarcoidosis uses pretest probability, how was that defined?
• Was cardiac MRI superior to PET in your study? Does one have to be first?
• How do experts decide how often to do follow up PET imaging in established cardiac sarcoidosis?
• What were areas of priority research that were identified?

The research study cited by Dr. Kafil was published on June 2, 2025. Click the following link to view the paper:

https://www.jacc.org/doi/full/10.1016/j.jcmg.2025.02.010

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

Anticoagulation Monotherapy in Patients with Chronic Coronary Artery Disease and Atrial Fibrillation

Anticoagulation Monotherapy in Patients with Chronic Coronary Artery Disease and Atrial Fibrillation

 

Guest: Keri Zieminski, APRN, C.N.P., D.N.P.

Host: Sharonne Hayes, M.D.

 

This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of anticoagulation monotherapy in patients with chronic CAD and atrial fibrillation. Discussion will include a brief overview of recently published trials that highlight the use of anticoagulation monotherapy in chronic CAD with atrial fibrillation, and how to manage a patient on anticoagulation monotherapy that needs to undergo noncardiac surgery. 

 

Topics Discussed:

• Why has there been a shift towards redefining antithrombotic medical therapy in patients with chronic CAD with atrial fibrillation? What's changed?
• Recently published trials that highlight the use of anticoagulation monotherapy in the chronic CAD + AF population.
• What is your process for managing a patient on anticoagulation monotherapy that needs to go for noncardiac surgery? 

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

Updated Guidelines for Perioperative Cardiovascular Management for Noncardiac Surgery

Updated Guidelines for Perioperative Cardiovascular Management for Noncardiac Surgery

 

Guest: Michael Cullen, M.D.

Host: Kyle Klarich, M.D.

 

This episode of Mayo Clinic’s “Interviews With the Experts” reviews the assessment of patients with known or suspected cardiovascular disease undergoing noncardiac surgery.  Dr. Michael Cullen discusses recommendations from 2024 ACC/AHA perioperative guidelines regarding medication management before and after noncardiac surgery, including recommendations for antiplatelet therapy and bridging anticoagulation.  Finally, he highlights new recommendations in the recent 2024 ACC/AHA perioperative guidelines and compare these guidelines to the 2022 European Society of Cardiology perioperative guidelines.

 

Topics Discussed:

• How should clinicians approach the assessment of a patient prior to noncardiac surgery?
• How should physicians and APPs manage cardiac medications around the time of noncardiac surgery?
• What are some of the new recommendations in the 2024 ACC/AHA guidelines for perioperative management prior to noncardiac surgery?
• How do the 2024 ACC/AHA perioperative guidelines differ from the 2022 ESC noncardiac surgery guidelines?

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

Obesity, Hypertension, and Risk Factors in Terms of Prevention and Decreasing the Risk of HfpEF

Obesity, Hypertension, and Risk Factors in Terms of Prevention and Decreasing the Risk of HfpEF

 

Guest: Affan Irfan, M.D., Ph.D.

Host: Stephen L. Kopecky, M.D.

 

HFpEF is a type of heart failure where the heart pumps normally but becomes stiff. This leads to fatigue, shortness of breath, and fluid retention. It is closely linked to obesity, hypertension, and metabolic disorders, with cases rising as these conditions become more common.

 

Topics Discussed:

• What is HFpEF and its risk factors?
• How common are obesity and hypertension, and how often do they lead to HFpEF?
• How do you diagnose HFpEF?
• How effective are weight loss, diet, and exercise in preventing HFpEF?
• What medical and public health strategies help reduce these risk factors and HFpEF cases?

  

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

Aortic Regurgitation: Beyond the Valve

Aortic Regurgitation: Beyond the Valve

 

Guest: Vidhu Anand, M.B.B.S.

Host: Kyle Klarich, M.D.

 

In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Klarich and Dr. Anand discuss evolving approaches to assessing left ventricular remodeling in chronic aortic regurgitation. Dr. Vidhu Anand discusses research showing that LV volumes, global longitudinal strain, and myocardial fibrosis can detect dysfunction earlier than traditional guideline thresholds. Listeners can expect to better understand the role of multimodality imaging, extra valvular involvement, and practical steps echocardiographers can take to optimize AR assessment. 

 

Topics Discussed:

• What imaging markers help detect early myocardial dysfunction in AR, and how do they assist in risk stratification?
• Guidelines traditionally focus on LV dimensions and ejection fraction for surgical decision-making in AR. Is there any data that guidelines may not be capturing patients at the optimal time?
• Is there a role of multimodality imaging in AR?

• What practical steps can a sonographer or echocardiographer today to bring their AR assessment closer to what your research suggests is optimal?  

 

Please reference Dr. Anand's research article(s) here:

https://pubmed.ncbi.nlm.nih.gov/39545891/

https://pubmed.ncbi.nlm.nih.gov/33253815/

https://pubmed.ncbi.nlm.nih.gov/39218370/

 

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

 

Podcast episode transcript found here.

Presentation, Evaluation, and Management of Premature Ventricular Contractions

Presentation, Evaluation, and Management of Premature Ventricular Contractions

 

Guest: Alan M. Sugrue, M.B., B.Ch., B.A.O.

Host: Anthony H. Kashou, M.D.

 

In this episode, Dr. Anthony Kashou and Dr. Alan Sugrue cover a practical, evidence-based approach to premature ventricular contractions (PVCs), from incidental findings to high-burden, high-risk presentations. Listeners will gain tools to differentiate benign from pathologic PVCs, understand when to monitor versus refer, and recognize the role of catheter ablation in improving outcomes.

 

Topics Discussed:

• PVCs show up on Holters and ECGs all the time — how do you decide when they matter?
• How often do PVCs cause cardiomyopathy, and when should we act?
• When should we consider ablation even if the patient is asymptomatic?
• What’s the biggest misconception about PVC ablation today?

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

Podcast episode transcript found here.