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The Cardiovascular CME podcast is a free educational offering from Mayo Clinic, featuring content geared towards physicians, physician assistants, and nurse practitioners who are interested in exploring a multitude of cardiology-related topics. Tune in and subscribe to explore today’s most pressing cardiology topics with your colleagues at Mayo Clinic and gain valuable insights that can be directly applied to your practice. No CME credit offered for podcast episodes at this time.
Episodes

Tuesday Jan 04, 2022
Tuesday Jan 04, 2022
Complicated Recurring Inflammatory Pericarditis: Role of Imaging and How to Treat
Guest: S. Allen Luis, M.B.B.S., Ph.D.
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
When recurrent chest pain episodes are confirmed to be complicated recurrent pericarditis (CRP) and resolution is challenging, considerations for choosing a referral center for treatment include the number of pericardiectomies being performed at the center and an understanding of the specific surgeon's recommended approach.
Joining us today to discuss CRP is S. Allen Luis, M.B.B.S., Ph.D., a cardiologist and director of the Pericardial Disease Clinic at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Definition, examples and frequency of CRP
- Ideal treatment for first-episode pericarditis
- Optimal management of CRP via tapering guided by inflammatory markers
- Role of echocardiography and cardiac MRI in the diagnosis of CRP
- New therapies and treatment algorithms for patients with CRP
- Side effects of interleukin-1 (IL-1) inhibitor therapy and use of azathioprine or intravenous immunoglobulin (IVIG) in the treatment of CRP
- How to evaluate centers when referring patients for radical pericardiectomy
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Dec 28, 2021
Stress Echocardiography
Tuesday Dec 28, 2021
Tuesday Dec 28, 2021
Stress Echocardiography
Guest: Patricia A. Pellikka, M.D. (@pattypellikka)
Host: Malcolm R. Bell, M.D.
Stress echocardiography is a unique and versatile technique recognized for its utility in the evaluation of nonischemic heart disease. In 2016, Patricia A. Pellikka, M.D., was one of the primary authors of the European Association of Cardiovascular Imaging (EACVI) and the American Society of Echocardiography (ASE) recommendations for the clinical use of stress echocardiography in nonischemic heart disease.
Joining us today to discuss stress echocardiography is Dr. Pellikka, a vice chair of Cardiovascular Medicine at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Origins of stress echocardiography and validation studies
- Accuracy of stress echocardiography related to pretest probability of disease in patient populations
- Use of contrast (image-enhancing agents) for diagnostic quality images
- Indications for stress echocardiography in patients with non-coronary artery disease
- Future directions for stress echocardiography, including myocardial perfusion
- Artificial intelligence applications in stress echocardiography
- Coronary computerized tomography angiography (CTA) versus stress echocardiography
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
Resource(s):
https://www.asecho.org/wp-content/uploads/2017/02/Stress-Echo-in-Non-Ischaemic-Guideline-2-2-17.pdf
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Thursday Dec 23, 2021
Coming Soon - ECG Segment: Making Waves
Thursday Dec 23, 2021
Thursday Dec 23, 2021
Join Dr. Kashou, a physician in Cardiology and fellow at Mayo Clinic in Rochester, Minnesota and other experts in the field of Electrocardiography as they discuss the latest developments and transformations in ECG monitoring.
Episodes will be released every other Thursday.
Stay tuned for the first episode on January 6, 2022.
Follow on social media:
Twitter: @MayoCVservices
Facebook: MayoCVservices
LinkedIn: Mayo Clinic Cardiovascular Services
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.

Tuesday Dec 21, 2021
Constrictive Pericarditis, Diagnosis and Management
Tuesday Dec 21, 2021
Tuesday Dec 21, 2021
Constrictive Pericarditis, Diagnosis and Management
Guest: Jae K. Oh, M.D. (@JaeKOh2)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
Pericardiectomy was the first cardiac surgery performed at Mayo Clinic, in 1935. Mayo's commitment to the treatment of constrictive pericarditis continues today. It's crucial that constrictive pericarditis be identified correctly because the disease is curable. With complete pericardiectomy, patients' heart failure can be cured.
Joining us today to discuss constrictive pericarditis is Jae K. Oh, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota. Dr. Oh is the founder and director of Mayo Clinic's Pericardial Disease Clinic.
Specific topics discussed:
- Mayo Clinic's commitment to medical and surgical expertise in the treatment of constrictive pericarditis
- The importance of diagnosis for pericardial constriction
- Patients with heart failure-type symptoms who present with liver failure
- Cardiac catheterization and echocardiographic hemodynamic imaging in the diagnosis of constrictive pericarditis
- Use of medical therapy and surgical treatment for patients with constrictive pericarditis
- Unusual complications seen in today's patients with constrictive pericarditis
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Dec 14, 2021
LAA Occlusion Device
Tuesday Dec 14, 2021
Tuesday Dec 14, 2021
LAA Occlusion Device
Guest: Mohamad Adnan (Mohamad) Alkhouli, M.D. (@adnanalkhouli)
Host: Paul A. Friedman, M.D. (@drpaulfriedman)
Left atrial appendage closure is an alternative to blood thinners for patients with atrial fibrillation who are at increased risk of stroke — but who are also intolerant of blood thinners for stroke prevention.
Joining us today to discuss the use of left atrial appendage occlusion devices for this select group of patients is Mohamad Adnan (Mohamad) Alkhouli, M.D., an interventional cardiologist at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Patient eligibility for left atrial appendage occlusion
- Therapies other than blood thinners for stroke prevention
- Results of surgery vs. transcatheter closure for patients with atrial fibrillation
- The patient experience with Mayo Clinic's minimally invasive approach
- Follow-up anticoagulation or dual antiplatelet therapy
- Reduced risk of blood clots forming on the occlusion device
- Advances in the field and related clinical trials
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Dec 07, 2021
Pulmonary Hypertension – When to Refer
Tuesday Dec 07, 2021
Tuesday Dec 07, 2021
Pulmonary Hypertension – When to Refer
Guest: Hilary M. DuBrock, M.D. (@hilarydubrockMD)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
It's important to consider pulmonary hypertension (PH) in the evaluation of patients with unexplained dyspnea. If a patient's echocardiogram shows a systolic pressure more than 50 mm HG, referral to a PH specialist for screening is crucial.
Joining us today to discuss PH is Hilary M. DuBrock, M.D., Pulmonary and Critical Care Medicine, at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Definition and classification of PH
- History, signs and symptoms that indicate a possible diagnosis of PH
- Initial screening indicators of PH
- Right-heart catheterization necessary for diagnosis
- When to consider referral to PH specialists
- Pitfalls for cardiologists to avoid in discussing a diagnosis of PH with patients
- Impact of other disorders on PH
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 30, 2021
Genetic Testing in Dilated Cardiomyopathy
Tuesday Nov 30, 2021
Tuesday Nov 30, 2021
Genetic Testing in Dilated Cardiomyopathy
Guest: Naveen L. Pereira, M.D. (@nl_pereira)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
It’s just a blood test — but genetic testing informs effective precision medicine-guided therapies for specific patients at high risk of sudden death and their family members.
Joining us today to discuss genetic testing for patients at risk of dilated cardiomyopathy is Naveen L. Pereira, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Genetics as a cause of dilated cardiomyopathy
- Screening and implications for family members
- Specific genes that put patients at high risk
- Sequencing panels that identify genes as benign, pathogenic or variants of uncertain significance
- Genetic counseling applications in practice
- Repeat testing recommendations
- Precision medicine-guided therapies
- Evolution of cost and insurance coverage
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 23, 2021
TTE Guidance for TAVR
Tuesday Nov 23, 2021
Tuesday Nov 23, 2021
TTE Guidance for TAVR
Guest: Jeremy J. Thaden, M.D. (@JeremyThaden)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
Due to a better understanding of valve sizing, deployment of valves coaxially, and technical advances in valves themselves, the majority of surgeries for patients requiring transcatheter aortic valve replacement (TAVR) at Mayo Clinic incorporate a transfemoral approach and moderate sedation, guided by transthoracic echocardiography (TTE).
Joining us today to discuss transthoracic echocardiographic guidance and a minimally invasive approach to transcatheter aortic valve implantation (TAVI) and TAVR is Jeremy J. Thaden, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Evolution of the role of transthoracic echocardiography in relation to TAVR
- Transthoracic echocardiographic guidance for patients receiving TAVR, incorporating a transfemoral approach and moderate sedation
- Rates of paravalvular aortic regurgitation risk reduction
- Minimal use of alternative approaches
- Key views for interventional echocardiographers related to paravalvular regurgitation imaging post-TAVR
- Mitral valve complications
- Other imaging for TAVR guidance
- Gradients in transcatheter aortic valve implantation (TAVI) and TAVR following procedures
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 16, 2021
High Altitude Heart Changes
Tuesday Nov 16, 2021
Tuesday Nov 16, 2021
The Heart in the Mountains: High Altitude Heart Changes
Guest: Bruce D. Johnson, Ph.D.
Host: Stephen L. Kopecky, M.D. (@DrSteveKopecky)
What happens to the human heart at high altitudes?
Joining us today to discuss research in human performance and the performance of the heart at high altitudes is Bruce D. Johnson, Ph.D., Cardiovascular Medicine and Preventive, Occupational and Aerospace Medicine at Mayo Clinic's campuses in Phoenix/Scottsdale, Arizona, and Rochester, Minnesota.
Specific topics discussed:
- The heart at high altitudes (8,000 to12,000 feet, or 2,400 to 3,700 meters)
- Oxygen saturation at high altitudes and the effect of sleep
- Myocardial blood flow at high altitudes
- Arrhythmias at high altitudes
- South Pole altitude study outcomes
- Risk factors for altitude sickness
- Peak altitude for human habitation (13,000 to 15,000 feet, or 4,000 to 4,600 meters)
- Impact of altitude on airplanes
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 09, 2021
How to Select the Right Aortic Valve
Tuesday Nov 09, 2021
Tuesday Nov 09, 2021
How to Select the Right Aortic Valve
Guest: Rick A. Nishimura, M.D.
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
Although choosing the right aortic valve for patients with aortic stenosis or aortic regurgitation is ultimately a shared decision-making process, there is now enough clinical trial data available to allow specialists to offer fully informed recommendations for the type of valve they'd recommend.
Joining us today to discuss how to select the right aortic valve is Rick A. Nishimura, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota, and recent co-chair of the writing committee updating the American College of Cardiology and American Heart Association guidelines on the management of valvular heart disease.
Specific topics discussed:
- Recommendations for patients at high risk for surgery and transcatheter aortic valve implantation (TAVI)
- Recommendations for patients at acceptable risk for surgery
- Impact of the patient's age
- Mechanical vs. tissue prostheses
- Older patients and the importance of shared decision making
- Younger patients should not receive TAVI
- Anatomic abnormalities that may prevent TAVI
- Valvular heart disease centers of excellence low rate of morbidity and mortality
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
No CME credit offered for this episode.
Podcast episode transcript found here.