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The Cardiovascular CME podcast is a free educational offering from Mayo Clinic, featuring content geared towards physicians, physician assistants, and nurse practitioners who are interested in exploring a multitude of cardiology-related topics. Tune in and subscribe to explore today’s most pressing cardiology topics with your colleagues at Mayo Clinic and gain valuable insights that can be directly applied to your practice. No CME credit offered for podcast episodes at this time.
Episodes

Tuesday Dec 21, 2021
Constrictive Pericarditis, Diagnosis and Management
Tuesday Dec 21, 2021
Tuesday Dec 21, 2021
Constrictive Pericarditis, Diagnosis and Management
Guest: Jae K. Oh, M.D. (@JaeKOh2)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
Pericardiectomy was the first cardiac surgery performed at Mayo Clinic, in 1935. Mayo's commitment to the treatment of constrictive pericarditis continues today. It's crucial that constrictive pericarditis be identified correctly because the disease is curable. With complete pericardiectomy, patients' heart failure can be cured.
Joining us today to discuss constrictive pericarditis is Jae K. Oh, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota. Dr. Oh is the founder and director of Mayo Clinic's Pericardial Disease Clinic.
Specific topics discussed:
- Mayo Clinic's commitment to medical and surgical expertise in the treatment of constrictive pericarditis
- The importance of diagnosis for pericardial constriction
- Patients with heart failure-type symptoms who present with liver failure
- Cardiac catheterization and echocardiographic hemodynamic imaging in the diagnosis of constrictive pericarditis
- Use of medical therapy and surgical treatment for patients with constrictive pericarditis
- Unusual complications seen in today's patients with constrictive pericarditis
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Dec 14, 2021
LAA Occlusion Device
Tuesday Dec 14, 2021
Tuesday Dec 14, 2021
LAA Occlusion Device
Guest: Mohamad Adnan (Mohamad) Alkhouli, M.D. (@adnanalkhouli)
Host: Paul A. Friedman, M.D. (@drpaulfriedman)
Left atrial appendage closure is an alternative to blood thinners for patients with atrial fibrillation who are at increased risk of stroke — but who are also intolerant of blood thinners for stroke prevention.
Joining us today to discuss the use of left atrial appendage occlusion devices for this select group of patients is Mohamad Adnan (Mohamad) Alkhouli, M.D., an interventional cardiologist at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Patient eligibility for left atrial appendage occlusion
- Therapies other than blood thinners for stroke prevention
- Results of surgery vs. transcatheter closure for patients with atrial fibrillation
- The patient experience with Mayo Clinic's minimally invasive approach
- Follow-up anticoagulation or dual antiplatelet therapy
- Reduced risk of blood clots forming on the occlusion device
- Advances in the field and related clinical trials
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Dec 07, 2021
Pulmonary Hypertension – When to Refer
Tuesday Dec 07, 2021
Tuesday Dec 07, 2021
Pulmonary Hypertension – When to Refer
Guest: Hilary M. DuBrock, M.D. (@hilarydubrockMD)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
It's important to consider pulmonary hypertension (PH) in the evaluation of patients with unexplained dyspnea. If a patient's echocardiogram shows a systolic pressure more than 50 mm HG, referral to a PH specialist for screening is crucial.
Joining us today to discuss PH is Hilary M. DuBrock, M.D., Pulmonary and Critical Care Medicine, at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Definition and classification of PH
- History, signs and symptoms that indicate a possible diagnosis of PH
- Initial screening indicators of PH
- Right-heart catheterization necessary for diagnosis
- When to consider referral to PH specialists
- Pitfalls for cardiologists to avoid in discussing a diagnosis of PH with patients
- Impact of other disorders on PH
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 30, 2021
Genetic Testing in Dilated Cardiomyopathy
Tuesday Nov 30, 2021
Tuesday Nov 30, 2021
Genetic Testing in Dilated Cardiomyopathy
Guest: Naveen L. Pereira, M.D. (@nl_pereira)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
It’s just a blood test — but genetic testing informs effective precision medicine-guided therapies for specific patients at high risk of sudden death and their family members.
Joining us today to discuss genetic testing for patients at risk of dilated cardiomyopathy is Naveen L. Pereira, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Genetics as a cause of dilated cardiomyopathy
- Screening and implications for family members
- Specific genes that put patients at high risk
- Sequencing panels that identify genes as benign, pathogenic or variants of uncertain significance
- Genetic counseling applications in practice
- Repeat testing recommendations
- Precision medicine-guided therapies
- Evolution of cost and insurance coverage
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 23, 2021
TTE Guidance for TAVR
Tuesday Nov 23, 2021
Tuesday Nov 23, 2021
TTE Guidance for TAVR
Guest: Jeremy J. Thaden, M.D. (@JeremyThaden)
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
Due to a better understanding of valve sizing, deployment of valves coaxially, and technical advances in valves themselves, the majority of surgeries for patients requiring transcatheter aortic valve replacement (TAVR) at Mayo Clinic incorporate a transfemoral approach and moderate sedation, guided by transthoracic echocardiography (TTE).
Joining us today to discuss transthoracic echocardiographic guidance and a minimally invasive approach to transcatheter aortic valve implantation (TAVI) and TAVR is Jeremy J. Thaden, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Evolution of the role of transthoracic echocardiography in relation to TAVR
- Transthoracic echocardiographic guidance for patients receiving TAVR, incorporating a transfemoral approach and moderate sedation
- Rates of paravalvular aortic regurgitation risk reduction
- Minimal use of alternative approaches
- Key views for interventional echocardiographers related to paravalvular regurgitation imaging post-TAVR
- Mitral valve complications
- Other imaging for TAVR guidance
- Gradients in transcatheter aortic valve implantation (TAVI) and TAVR following procedures
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 16, 2021
High Altitude Heart Changes
Tuesday Nov 16, 2021
Tuesday Nov 16, 2021
The Heart in the Mountains: High Altitude Heart Changes
Guest: Bruce D. Johnson, Ph.D.
Host: Stephen L. Kopecky, M.D. (@DrSteveKopecky)
What happens to the human heart at high altitudes?
Joining us today to discuss research in human performance and the performance of the heart at high altitudes is Bruce D. Johnson, Ph.D., Cardiovascular Medicine and Preventive, Occupational and Aerospace Medicine at Mayo Clinic's campuses in Phoenix/Scottsdale, Arizona, and Rochester, Minnesota.
Specific topics discussed:
- The heart at high altitudes (8,000 to12,000 feet, or 2,400 to 3,700 meters)
- Oxygen saturation at high altitudes and the effect of sleep
- Myocardial blood flow at high altitudes
- Arrhythmias at high altitudes
- South Pole altitude study outcomes
- Risk factors for altitude sickness
- Peak altitude for human habitation (13,000 to 15,000 feet, or 4,000 to 4,600 meters)
- Impact of altitude on airplanes
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 09, 2021
How to Select the Right Aortic Valve
Tuesday Nov 09, 2021
Tuesday Nov 09, 2021
How to Select the Right Aortic Valve
Guest: Rick A. Nishimura, M.D.
Host: Kyle W. Klarich, M.D. (@KyleWKlarich)
Although choosing the right aortic valve for patients with aortic stenosis or aortic regurgitation is ultimately a shared decision-making process, there is now enough clinical trial data available to allow specialists to offer fully informed recommendations for the type of valve they'd recommend.
Joining us today to discuss how to select the right aortic valve is Rick A. Nishimura, M.D., a cardiologist at Mayo Clinic in Rochester, Minnesota, and recent co-chair of the writing committee updating the American College of Cardiology and American Heart Association guidelines on the management of valvular heart disease.
Specific topics discussed:
- Recommendations for patients at high risk for surgery and transcatheter aortic valve implantation (TAVI)
- Recommendations for patients at acceptable risk for surgery
- Impact of the patient's age
- Mechanical vs. tissue prostheses
- Older patients and the importance of shared decision making
- Younger patients should not receive TAVI
- Anatomic abnormalities that may prevent TAVI
- Valvular heart disease centers of excellence low rate of morbidity and mortality
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 02, 2021
SCAD-Update on Diagnosis and Treatment
Tuesday Nov 02, 2021
Tuesday Nov 02, 2021
SCAD-Update on Diagnosis and Treatment
Guest: Sharonne N. Hayes, M.D. (@SharonneHayes)
Host: Stephen L. Kopecky, M.D. (@DrSteveKopecky)
Spontaneous coronary artery dissection (SCAD) was traditionally understood to be a rare syndrome that only happened to women who were pregnant or early postpartum and was almost universally fatal. That understanding has changed as research has become more focused on heart disease in women.
Joining us today to discuss current SCAD diagnosis and treatment is Sharonne N. Hayes, M.D., a preventive cardiologist at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Evolution of the understanding of SCAD
- SCAD defined
- Differentiation of SCAD from other acute coronary syndromes
- Diagnosis and treatment
- Impact of statins
- Family screening
- Lifestyle modifications
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Oct 26, 2021
COVID 19 in the CICU
Tuesday Oct 26, 2021
Tuesday Oct 26, 2021
COVID 19 in the CICU
Guest: Courtney E. Bennett, D.O.
Host: Malcolm R. Bell, M.D.
The data is strong: Patients with known cardiovascular disease or other risk factors for cardiovascular disease are at increased risk of COVID-19 infection. Patients with COVID-19 and underlying cardiovascular disease are sicker and require more ICU-level care than patients without cardiovascular risk factors. Those factors include hypertension, diabetes and obesity.
Joining us today to discuss COVID-19 and cardiovascular disease is Courtney E. Bennett, D.O., a cardiologist and the director of the cardiac intensive care unit at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Heightened risk of COVID-19 infection in patients with preexisting cardiovascular disease and impact on prognosis
- Manifestations that identify patients as having myocardial insult or injury
- Magnitude of troponin rises in these patients who may have septic shock or severe respiratory distress
- The role of electrocardiogram (ECG) for patients with ST depression
- Treatment for patients with ST elevation
- Anticoagulation treatment for patients with acute coronary syndrome (ACS)
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Oct 19, 2021
Ceramides as a New Biomarker for Cardiovascular Risk Prediction
Tuesday Oct 19, 2021
Tuesday Oct 19, 2021
Ceramides as a New Biomarker for Cardiovascular Risk Prediction
Guest: Vlad C. Vasile, M.D., Ph.D. (@VladCVasile)
Host: Stephen L. Kopecky, M.D. (@DrSteveKopecky)
Ceramides are lipids that are ubiquitously expressed. They are present in all cell membranes. Some ceramides have been associated with risk of atherosclerotic disease in patients with known coronary artery disease. Researchers at Mayo Clinic and others have demonstrated that ceramides can also predict negative events in patients without known coronary artery disease.
Joining us today to discuss ceramides is Vlad C. Vasile, M.D., Ph.D., a preventive cardiologist and co-director of Cardiovascular Laboratory Medicine at Mayo Clinic in Rochester, Minnesota.
Specific topics discussed:
- Ceramides and the ceramide score blood test
- Primary and secondary risk assessment for atherosclerotic events
- Using ceramide score in patients at intermediate risk
- Score modification via diet, exercise and lipid-lowering agents
- Testing for lipoprotein (a)
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
No CME credit offered for this episode.
Podcast episode transcript found here.