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The Cardiovascular CME podcast is a new educational offering from Mayo Clinic, featuring content geared towards physicians, physician assistants, and nurse practitioners who are interested in exploring a multitude of cardiology-related topics. Tune in and subscribe to explore today’s most pressing cardiology topics with your colleagues at Mayo Clinic and gain valuable insights that can be directly applied to your practice. No CME credit offered for podcast episodes at this time.
Episodes

Tuesday May 02, 2023
Adults after the Fontan Operation: Which Medications Work?
Tuesday May 02, 2023
Tuesday May 02, 2023
Adults after the Fontan Operation: Which Medications Work?
Guest: Alexander C. Egbe, M.B.B.S., M.P.H.
Host: Luke J. Burchill, M.B.B.S., Ph.D.
Joining us today to discuss which medications work for adults after the Fontan operation is, Alexander C. Egbe, M.B.B.S., M.P.H., professor of medicine and structural heart disease specialist in the department of cardiovascular medicine at Mayo Clinic in Rochester, Minnesota. Tune in to learn more about the Fontan operation and which medications work.
Specific topics discussed:
- What are the medical problems common in the adult Fontan population?
- Which medical therapies are currently available to address these comorbidities?
- How effective at these medications? What are areas of improvement and further research?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Thursday Apr 27, 2023
STEMI/NSTEMI and OMI/NOMI Paradigms
Thursday Apr 27, 2023
Thursday Apr 27, 2023
STEMI/NSTEMI and OMI/NOMI Paradigms
Guest: Stephen W. Smith, M.D.
Host: Anthony H. Kashou, M.D.
Early detection of acute myocardial infarction (MI) can impact patients' immediate care and long-term outcomes. Most trained physicians can detect common ST-elevation MI (STEMI) patterns on ECG. However, a subset of patients does not present with common STEMI patterns. There are ECG patterns that can be identified to improve patient outcomes but are not yet widely known or accepted in current guidelines.
Joining us today to discuss the STEMI versus non-STEMI (NSTEMI) and occlusion MI (OMI) versus nonocclusion MI (NOMI) paradigms is Stephen W. Smith, M.D., Emergency Medicine, Hennepin Healthcare, in Minneapolis.
Specific topics discussed:
- The problem with the STEMI versus NSTEMI dichotomy
- Subgroup within the NSTEMI cohort that may benefit from emergent reperfusion therapy
- ECG findings to watch for — beyond, standard STEMI findings — that indicate an occluded artery
- Access to Dr. Smith's evaluation formula
- Patterns to watch for in diagnosis of OMI
- Benign mimickers
- Key takeaways for the novice interpreter
- Other clinical factors to watch for that may indicate OMI
- Recommendations for emergency medicine providers
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
No CME available for this episode.
Transcript found here.
Original Release Date: 3/31/22

Tuesday Apr 25, 2023
COVID-19 Infection and Vaccination: Understanding the Prothrombotic Risk
Tuesday Apr 25, 2023
Tuesday Apr 25, 2023
COVID-19 Infection and Vaccination: Understanding the Prothrombotic Risk
Guest: Damon E. Houghton, M.D., M.S.
Host: Malcolm R. Bell, M.D.
Joining us today to discuss COVID-19 infection and vaccination and understanding what the prothrombotic risk is, Damon E. Houghton, M.D., M.S., associate professor of medicine and vascular medicine specialist in the department of cardiovascular medicine at Mayo Clinic in Rochester, Minnesota. Tune in to learn more about the prothrombotic risk in patients with COVID-19 infection and vaccination.
Specific topics discussed:
- What have we learned about the risk for thrombosis associated with COVID-19 infections?
- Recognizing the increased risk of thrombosis in some patients, what is the role of anti-thrombotic medications for prevention?
- In April of 2021, the CDC and FDA paused administration of the Janssen (J&J) vaccination temporarily due to strange cases of thrombosis and thrombocytopenia, what do we now know about COVID-19 vaccinations and this adverse reaction?
Venous Thromboembolism (VTE) risk in the 90 days after COVID-19 infection graph.
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Apr 18, 2023
Treating Heart Failure in Adults with Congenital Heart Disease: Heart Transplant
Tuesday Apr 18, 2023
Tuesday Apr 18, 2023
Treating Heart Failure in Adults with Congenital Heart Disease: Heart Transplant
Guest: Mauricio A. Villavicencio Theoduloz, M.D.
Host: Luke J. Burchill, M.B.B.S., Ph.D.
Joining us today to discuss heart transplant in patients with congenital heart disease (CHD) is Mauricio A. Villavicencio Theoduloz, M.D., associate professor of surgery and Director of Heart and Lung Transplant at Mayo Clinic in Rochester, Minnesota. Tune in to learn more about the surgical approach to heart transplant in patients with CHD.
Specific topics discussed:
- Are we seeing more and more of these patients?
- What do you say to patients and families the first time you're meeting them to discuss the possibility of transplant?
- When is the timing right and who is the ideal candidate for transplant? Can you explain who is likely to benefit from transplant?
- Can you explain heart after liver transplant and why we go in that direction and why are we now doing that here at Mayo Clinic?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Thursday Apr 13, 2023
AI-ECG to Detect Cardiac Amyloidosis: Strengths, Limitations, and Future Directions
Thursday Apr 13, 2023
Thursday Apr 13, 2023
AI-ECG to Detect Cardiac Amyloidosis: Strengths, Limitations, and Future Directions
Guests: David M. Harmon, Jr. M.D.
Hosts: Anthony H. Kashou, M.D. (@anthonykashoumd)
Joining us today to discuss using AI-ECG to detect cardiac amyloidosis is David M. Harmon, Jr. M.D., cardiology fellow at Mayo Clinic Rochester, Minnesota. Dr. Harmon’s research interests include the clinical application of artificial intelligence electrocardiography and assessing the utility of AI algorithms on wearable devices. Tune in to learn about using AI-ECG to detect cardiac amyloidosis.
Specific topics discussed:
- Can you share a little background as to why AI-ECG for cardiac amyloidosis screening?
- What are some of the most surprising results of your validation study?
- What are the biggest limitations you found in this work?
- What are some next steps for this algorithm?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
Facebook: MayoCVservices
LinkedIn: Mayo Clinic Cardiovascular Services
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Apr 11, 2023
Transcatheter Aortic Valve Replacement (TAVR) vs. Aortic Valve Replacement (AVR)
Tuesday Apr 11, 2023
Tuesday Apr 11, 2023
Transcatheter Aortic Valve Replacement (TAVR) vs. Aortic Valve Replacement (AVR)
Guest: Kevin L. Greason, M.D.
Host: Kyle W. Klarich, M.D.
Joining us today to discuss Transcatheter Aortic Valve Replacement (TAVR) versus Aortic Valve Replacement (AVR) is Kevin Greason, M.D., associate professor of surgery and cardiac surgeon at Mayo Clinic Rochester, Minnesota. Tune in to learn more about the surgical differences between TAVR and AVR.
Specific topics discussed:
- What are the main advantages of TAVR? What are the main advantages of SAVR?
- How do you select patients for one treatment or another?
- What are the advantages of mechanical valves and when do you use them?
- What is the durability of TAVR and SAVR? Rate of reoperation/reintervention?
- What treatment do you recommend for a young patient with aortic stenosis?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Apr 04, 2023
Coronary Revascularization
Tuesday Apr 04, 2023
Tuesday Apr 04, 2023
Coronary Revascularization
Guest: John M. Stulak, M.D.
Host: Malcolm R. Bell, M.D.
Joining us today to discuss coronary revascularization is John Stulak, M.D., professor of surgery and cardiac surgeon at Mayo Clinic Rochester, Minnesota. Tune in to learn more about the surgical approach to coronary revascularization.
Specific topics discussed:
- Current era of CABG, trends, status of the practice
- Alternate approaches – hybrid, off pump. Robotic/minimally invasive
- Conduit choices, multiple arterial revascularization
- Future state
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Thursday Mar 30, 2023
Reduced Lead Setting for Diagnostic ECG Interpretation Using Deep Learning Models
Thursday Mar 30, 2023
Thursday Mar 30, 2023
Reduced Lead Setting for Diagnostic ECG Interpretation Using Deep Learning Models
Guests: Joel Xue, Ph.D.
Hosts: Anthony H. Kashou, M.D. (@anthonykashoumd)
Joining us today to discuss what reduced-lead ECG analysis is, it's clinical value, some of its challenges, and how it compares to standard 12-lead ECG analysis is Joel Xue, Ph.D. Dr. Xue currently leads the AI group of AliveCor and is an adjunct professor of Bioinformatics department at Emory University, Atlanta, Georgia. Tune in to learn about using Deep learning models to reduce lead setting for diagnostic ECG interpretation.
Specific topics discussed:
- What is reduced-12-lead ECG, and what is its clinical value?
- What are the main challenges for the reduced lead ECG analysis?
- How the Deep learning model method can be applied to reduced lead ECG analysis?
- Are the analysis performance comparable to the standard 12-lead ECG analysis?
- Next steps R&D and clinical use.
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
Facebook: MayoCVservices
LinkedIn: Mayo Clinic Cardiovascular Services
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Mar 28, 2023
Minimally Invasive Cardiac Surgery
Tuesday Mar 28, 2023
Tuesday Mar 28, 2023
Minimally Invasive Cardiac Surgery
Guest: Malakh L. Shrestha, M.B.B.S., Ph.D.
Host: Kyle W. Klarich, M.D.
Joining us today to discuss minimally invasive cardiac surgery is Malakh L. Shrestha, M.B.B.S., Ph.D., cardiac surgeon at Mayo Clinic Rochester, Minnesota. Dr. Shrestha was recruited from Germany and starting a Center for Excellence for Aortic Disease at Mayo Clinic; he also contributed to the American Association of Thoracic Surgery (AATS) guidelines for aortic dissection. Tune in to learn more about minimally invasive cardiac surgery.
Specific topics discussed:
- Present status of Aortic valve repair
- Durability and peri-operative risks
- Is minimally Invasive Aortic valve repair possible?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Mar 21, 2023
What is a Cardio-Protective Diet?
Tuesday Mar 21, 2023
Tuesday Mar 21, 2023
What is a Cardio-Protective Diet?
Guest: Kyla M. Lara-Breitinger, M.D.
Host: Malcolm R. Bell, M.D.
Joining us today to discuss cardio-protective diet is Kyla M. Lara-Breitinger, M.D., instructor in medicine in preventive cardiology at Mayo Clinic Rochester, Minnesota. Tune in to learn more about a cardio-protective diet.
Specific topics discussed:
- What determines a cardio-protective diet?
- Is there a best cardioprotective diet to follow out there based on scientific data?
- There are many controversies out there like the egg debate, dairy debate, ketogenic, and low-fat diets. What do you say to patients that ask you these specific questions in clinic?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV.
NEW Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.