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The Cardiovascular CME podcast is a free educational offering from Mayo Clinic, featuring content geared towards physicians, physician assistants, and nurse practitioners who are interested in exploring a multitude of cardiology-related topics.
Tune in and subscribe to explore today’s most pressing cardiology topics with your colleagues at Mayo Clinic and gain valuable insights that can be directly applied to your practice.
No CME credit offered for podcast episodes at this time.
Episodes

Tuesday Oct 14, 2025
2024 Peripheral Arterial Guidelines: What’s New
Tuesday Oct 14, 2025
Tuesday Oct 14, 2025
2024 Peripheral Arterial Guidelines: What’s New
Guest: Stan Henkin, M.D.
Host: Malcolm Bell, M.D.
The new iteration of ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS Guideline for the Management of Lower Extremity Peripheral Artery Disease came out in 2024, providing multiple new recommendations for the management of lower extremity peripheral artery disease (PAD) as compared to the 2016 PAD Guideline. These recommendations were made in light of multiple new trials since the prior guideline, including use of antiplatelet and antithrombotic therapy, lipid-lowering therapy and structured exercise therapy. For the first time, these guidelines also underscore the importance of health disparities in PAD. This podcast will highlight these new recommendations with focus on prevention of adverse events in patients with PAD.
Topics Discussed:
- Why was an update of 2016 PAD guidelines necessary?
- What are important new class I recommendations in the guidelines?
- For the first time, health disparities are highlighted for patients with PAD. Why was this done?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Oct 07, 2025
Patients Struggling With SVT/AVNRT and Catheter Ablation
Tuesday Oct 07, 2025
Tuesday Oct 07, 2025
Patients Struggling With SVT/AVNRT and Catheter Ablation
Guest: Christopher DeSimone, M.D., Ph.D.
Host: Anthony H. Kashou, M.D.
In this episode, Dr. Anthony Kashou and Dr. Christopher DeSimone dive into the challenges patients face with supraventricular tachycardia (SVT) and atrioventricular nodal reentrant tachycardia (AVNRT). They explore treatment options ranging from medications to catheter ablation, highlighting how these approaches aim to improve quality of life. Listeners will learn what to expect during an ablation procedure, including safety, anesthesia, and risks. Most importantly, they discuss how patients can feel empowered to make informed decisions about their care and reclaim confidence in their health.
Topics Discussed:
- Options and goals of current treatment options for AVNRT/SVT
- Catheter ablation as a means to treat and cure AVNRT/SVT
- What to expect and what will occur during AVNRT ablation
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 30, 2025
Effects of Social Isolation and Loneliness on the Heart
Tuesday Sep 30, 2025
Tuesday Sep 30, 2025
Effects of Social Isolation and Loneliness on the Heart
Guest: Amir Lerman, M.D.
Host: Stephen L. Kopecky, M.D.
Social isolation and loneliness are common, mainly in the elderly, and are regarded as major cardiovascular risk factors. The factors are associated with an increase in cardiovascular events and mortality. Additionally, social isolation and loneliness are associated with increased systemic inflammation and progression of atherosclerosis
Topics Discussed:
- How do you identify social isolation?
- Mechanism of social isolation and loneliness on CV health
- Prevalences and risk of social isolation and loneliness
- Findings of a recent study from Mayo Clinic
- Case story: the Roseto effect
- Potential therapy
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 23, 2025
Ischemia with No Obstructive Arteries (INOCA) in 2024
Tuesday Sep 23, 2025
Tuesday Sep 23, 2025
Ischemia with No Obstructive Arteries (INOCA) in 2024
Guest: Claire Raphael, M.B.B.S., Ph.D.
Host: Sharonne Hayes, M.D.
INOCA is a common condition. It is an acronym that stands for ischemia with non-obstructive coronary artery disease. We discuss when to consider a diagnosis of INOCA, how to diagnose it and how to treat patients.
Topics Discussed:
- What is INOCA?
- Who is at risk for INOCA?
- How do we manage INOCA?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 16, 2025
Statin Myopathy
Tuesday Sep 16, 2025
Tuesday Sep 16, 2025
Statin Myopathy
Guest: Stephen Kopecky, M.D.
Host: Sharonne Hayes, M.D.
Statins are very helpful to lower LDL cholesterol and subsequently lower cardiovascular risk. Studies of statins have excluded subjects that are statin intolerant which is usually due to muscle symptoms such as aches, called myalgias, muscle cramps, or weakness. One of the most significant predictors of statin intolerance is the dose -the higher the dose, the more likely to develop intolerance. Accepted in recommended ways to minimize intolerance is to use generic combination therapy with a lower dose statin and a cholesterol absorption inhibiting agent such as ezetimibe. Newer agents such as PCS K 9 inhibitors and inclisiran, both given subQ, and bempedoic acid may reduce statin muscle symptoms.
Topics Discussed:
- Is any statin more or less likely to cause statin associated muscle symptoms?
- Are there any protective medications that can minimize statin myalgias?
- What newer non-statin agents have been shown to reduce risk of myalgias?
- How is treating high cholesterol levels becoming more like treating blood pressure?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 09, 2025
Recent Updates in AF Guidelines
Tuesday Sep 09, 2025
Tuesday Sep 09, 2025
Recent Updates in AF Guidelines
Guest: Christopher DeSimone, M.D., Ph.D.
Guest: Abhishek Deshmukh, M.B.B.S.
Host: Anthony H. Kashou, M.D.
There have been several recent publications from major societies (ACC/HRS/EHRA/ESC) regarding atrial fibrillation management updates. These include updates to treatment interventions in patients with AFib such as catheter ablation, medical therapy, heart failure, and timing of intervention.
Topics Discussed:
- What are the new recommendations on catheter ablation?
- What is new regarding the relationship between atrial fibrillation and heart failure?
- Are there new guidelines on Intervention and timing in atrial fibrillation management?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 02, 2025
Tuesday Sep 02, 2025
Patient Selection and the Role of Echo Imaging for Tricuspid Structural Heart Procedures
Guest: Jeremy Thaden, M.D.
Host: Paul Friedman, M.D.
This podcast will give an overview of the growth of transcatheter structural heart procedures in recent years and the co-evolution of structural heart imaging (echocardiography) for patient selection and guidance.
Topics Discussed:
- Mayo’s experience with transcatheter structural heart procedures
- How has echo imaging evolved to facilitate guidance of structural heart procedures?
- What advice can you give for those interested in structural heart imaging?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Aug 26, 2025
Tuesday Aug 26, 2025
What is ECG Age Vs. Chronological age, and How to Use it in Your CV Prevention Practice
Guest: Francisco Lopez-Jimenez, M.D., M.S.
Host: Stephen L. Kopecky, M.D.
After listening to this episode of the CV Prevention segment of Mayo Clinic’s podcast “Interviews with the Experts,” listeners will better understand why it is important to differentiate between biological and chronological age. This is something that may help identify increased risk for age-related conditions and factors that may adversely affecting a person’s health. Listeners will become familiar with different ways to measure aging rate or biological age, especially with ECG age. Finally, factors that appear to affect biological age, such as social determinants of health, lack of exercise, excess weight, and stress are discussed.
Topics Discussed:
- What is ECG Age?
- How did your team come up with the idea?
- Why is important to differentiate between biological age and chronological age?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Aug 19, 2025
Robotic Cardiac Surgery
Tuesday Aug 19, 2025
Tuesday Aug 19, 2025
Robotic Cardiac Surgery
Guest: Phillip Rowse, M.D.
Guest: Marty Unruh, APRN, C.N.P., D.N.P.
Host: Kyle Klarich, M.D.
In this episode of “Interviews With the Experts,” listeners will hear a discussion on the most important questions patients should ask as they consider whether or not to pursue a robotic-assisted approach for surgical treatment of their valvular heart disease. It is clarified how robotic heart surgery works, including associated risks, benefits, and misconceptions. And finally, there is a discussion on the expected short- and long-term results of robotic heart valve surgery.
Topics Discussed:
- What types of procedures can be performed robotically, and how does robotic surgery compare to traditional and other minimally invasive techniques?
- Who qualifies for robotic surgery, and is it safe and effective?
- What testing is needed beforehand, what is the typical recovery time, and how long is the hospital stay and return-to-work timeline?
- Do surgeons perform the procedure or does the robot operate independently?
- How many robotic surgeries has Mayo Clinic performed, and what are the benefits compared to open-heart surgery (sternotomy)?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Aug 12, 2025
Anticoagulation with AF and Cancer
Tuesday Aug 12, 2025
Tuesday Aug 12, 2025
Anticoagulation with AF and Cancer
Guest: Nicholas Tan, M.D., M.S.
Host: Anthony H. Kashou, M.D.
In today’s episode of ECG Making Waves, Dr. Anthony Kashou interviews Dr. Nicholas Tan on how to manage anticoagulation in patients with cancer. They discuss the importance of appreciating the challenging balance in managing stroke risk in patients with cancer and atrial fibrillation. After listening to this episode, listeners will understand alternative strategies for stroke prevention in addition to systemic anticoagulation.
Topics Discussed:
- What is the relationship between cancer and atrial fibrillation?
- Why is stroke prevention challenging in this situation?
- What is the role of left atrial appendage closure in cancer patients?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
