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The Cardiovascular CME podcast is a free educational offering from Mayo Clinic, featuring content geared towards physicians, physician assistants, and nurse practitioners who are interested in exploring a multitude of cardiology-related topics.
Tune in and subscribe to explore today’s most pressing cardiology topics with your colleagues at Mayo Clinic and gain valuable insights that can be directly applied to your practice.
No CME credit offered for podcast episodes at this time.
Episodes

Tuesday Nov 11, 2025
Evolving Treatment Landscape in Transthyretin Cardiac Amyloidosis
Tuesday Nov 11, 2025
Tuesday Nov 11, 2025
Evolving Treatment Landscape in Transthyretin Cardiac Amyloidosis
Guest: Rosalyn Adigun, M.D., Pharm.D.
Host: S. Allen Luis, M.B.B.S., Ph.D.
In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Allen Luis interviews Dr. Rosalyn Adigun on transthyretin cardiac amyloidosis. Listeners will come away with a detailed overview of the evolution of treatment options for patient diagnosed with transthyretin amyloid cardiomyopathy, highlighting historical perspectives, early registration studies, current treatment options, and an outlook on future directions in the management of transthyretin cardiac amyloidosis.
Topics Discussed:
- Overview of the historical perspectives on the diagnosis and management of transthyretin amyloidosis.
- Current treatment options available for transthyretin amyloid cardiomyopathy, and factors that should guide a clinician's decision regarding the choice of therapy.
- Treatment options in the coming years.
- Ongoing research initiatives in the management of cardiac amyloidosis.
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Nov 04, 2025
Radiation Therapy and its Effect on the Heart and Cardiac Devices
Tuesday Nov 04, 2025
Tuesday Nov 04, 2025
Radiation Therapy and its Effect on the Heart and Cardiac Devices
Guest: Nicholas Tan, M.D., M.S.
Host: Anthony H. Kashou, M.D.
Mayo Clinic electrophysiologist Dr. Nicholas Tan joins Dr. Anthony Kashou on this episode of “ECG Making Waves” to discuss how radiation therapy can impact the heart and heart rhythm. After listening to this podcast, listeners will have developed awareness of the complexities behind managing cardiac devices in cancer patients.
Topics Discussed:
- What effect does radiation therapy have on the heart?
- What arrhythmias can be seen with radiation therapy?
- How can radiation therapy impact cardiac device management?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Oct 28, 2025
When to Consider Intervention for Peripheral Arterial Disease
Tuesday Oct 28, 2025
Tuesday Oct 28, 2025
When to Consider Intervention for Peripheral Arterial Disease
Guest: Stan Henkin, M.D.
Host: Malcolm Bell, M.D.
Although optimal medical therapy is key to decrease the risk of major adverse cardiac events in patients with peripheral artery disease (PAD), lower extremity arterial revascularization also plays an important role in management of symptoms and prevention of amputation. Thus, it is important to recognize the optimal timing for patient to be referred for lower extremity arterial revascularization. This podcast will discuss when patients with established PAD should be considered for peripheral revascularization.
Topics Discussed:
- Can you tell us about clinical subsets of PAD and what symptoms may be expected with each subset?
- Recent BEST-CLI trial garnered a lot of attention and press. Can you tell us more about this trial and why results are important for treatment of patients with CLTI?
- When should a patient with claudication be referred for revascularization?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Oct 21, 2025
Heart Healthy Diet: How to Evaluate Your Patients
Tuesday Oct 21, 2025
Tuesday Oct 21, 2025
Heart Healthy Diet: How to Evaluate Your Patients
Guest: Kyla Lara-Breitinger, M.D.
Host: Stephen L. Kopecky, M.D.
Nutrition counseling plays a vital role in cardiovascular care, and even brief conversations can make a meaningful impact. Rapid dietary screeners offer a practical way to assess how heart healthy a patient’s eating pattern is, helping providers initiate valuable discussions. While no single cardioprotective diet stands above the rest, emphasizing reduced intake of ultra-processed foods and ensuring adequate protein—primarily from plant-based sources and lean animal proteins like poultry, fish, and seafood—can support heart health. These dietary priorities become especially important in later life stages, when maintaining lean muscle mass is critical to reducing risks of frailty, morbidity, and mortality.
- How do you evaluate whether your patient is following a heart healthy dietary pattern?
- What makes a cardioprotective diet different from other diets?
- Is there a best diet or go-to-diet that is superior to all?
- When discussing nutrition with patients, what key advice should you prioritize?
Easily check your diet with mini-eat.org as discussed by Dr. Lara-Breitinger and Dr. Kopecky!
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Oct 14, 2025
2024 Peripheral Arterial Guidelines: What’s New
Tuesday Oct 14, 2025
Tuesday Oct 14, 2025
2024 Peripheral Arterial Guidelines: What’s New
Guest: Stan Henkin, M.D.
Host: Malcolm Bell, M.D.
The new iteration of ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS Guideline for the Management of Lower Extremity Peripheral Artery Disease came out in 2024, providing multiple new recommendations for the management of lower extremity peripheral artery disease (PAD) as compared to the 2016 PAD Guideline. These recommendations were made in light of multiple new trials since the prior guideline, including use of antiplatelet and antithrombotic therapy, lipid-lowering therapy and structured exercise therapy. For the first time, these guidelines also underscore the importance of health disparities in PAD. This podcast will highlight these new recommendations with focus on prevention of adverse events in patients with PAD.
Topics Discussed:
- Why was an update of 2016 PAD guidelines necessary?
- What are important new class I recommendations in the guidelines?
- For the first time, health disparities are highlighted for patients with PAD. Why was this done?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Oct 07, 2025
Patients Struggling With SVT/AVNRT and Catheter Ablation
Tuesday Oct 07, 2025
Tuesday Oct 07, 2025
Patients Struggling With SVT/AVNRT and Catheter Ablation
Guest: Christopher DeSimone, M.D., Ph.D.
Host: Anthony H. Kashou, M.D.
In this episode, Dr. Anthony Kashou and Dr. Christopher DeSimone dive into the challenges patients face with supraventricular tachycardia (SVT) and atrioventricular nodal reentrant tachycardia (AVNRT). They explore treatment options ranging from medications to catheter ablation, highlighting how these approaches aim to improve quality of life. Listeners will learn what to expect during an ablation procedure, including safety, anesthesia, and risks. Most importantly, they discuss how patients can feel empowered to make informed decisions about their care and reclaim confidence in their health.
Topics Discussed:
- Options and goals of current treatment options for AVNRT/SVT
- Catheter ablation as a means to treat and cure AVNRT/SVT
- What to expect and what will occur during AVNRT ablation
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 30, 2025
Effects of Social Isolation and Loneliness on the Heart
Tuesday Sep 30, 2025
Tuesday Sep 30, 2025
Effects of Social Isolation and Loneliness on the Heart
Guest: Amir Lerman, M.D.
Host: Stephen L. Kopecky, M.D.
Social isolation and loneliness are common, mainly in the elderly, and are regarded as major cardiovascular risk factors. The factors are associated with an increase in cardiovascular events and mortality. Additionally, social isolation and loneliness are associated with increased systemic inflammation and progression of atherosclerosis
Topics Discussed:
- How do you identify social isolation?
- Mechanism of social isolation and loneliness on CV health
- Prevalences and risk of social isolation and loneliness
- Findings of a recent study from Mayo Clinic
- Case story: the Roseto effect
- Potential therapy
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 23, 2025
Ischemia with No Obstructive Arteries (INOCA) in 2024
Tuesday Sep 23, 2025
Tuesday Sep 23, 2025
Ischemia with No Obstructive Arteries (INOCA) in 2024
Guest: Claire Raphael, M.B.B.S., Ph.D.
Host: Sharonne Hayes, M.D.
INOCA is a common condition. It is an acronym that stands for ischemia with non-obstructive coronary artery disease. We discuss when to consider a diagnosis of INOCA, how to diagnose it and how to treat patients.
Topics Discussed:
- What is INOCA?
- Who is at risk for INOCA?
- How do we manage INOCA?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 16, 2025
Statin Myopathy
Tuesday Sep 16, 2025
Tuesday Sep 16, 2025
Statin Myopathy
Guest: Stephen Kopecky, M.D.
Host: Sharonne Hayes, M.D.
Statins are very helpful to lower LDL cholesterol and subsequently lower cardiovascular risk. Studies of statins have excluded subjects that are statin intolerant which is usually due to muscle symptoms such as aches, called myalgias, muscle cramps, or weakness. One of the most significant predictors of statin intolerance is the dose -the higher the dose, the more likely to develop intolerance. Accepted in recommended ways to minimize intolerance is to use generic combination therapy with a lower dose statin and a cholesterol absorption inhibiting agent such as ezetimibe. Newer agents such as PCS K 9 inhibitors and inclisiran, both given subQ, and bempedoic acid may reduce statin muscle symptoms.
Topics Discussed:
- Is any statin more or less likely to cause statin associated muscle symptoms?
- Are there any protective medications that can minimize statin myalgias?
- What newer non-statin agents have been shown to reduce risk of myalgias?
- How is treating high cholesterol levels becoming more like treating blood pressure?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.

Tuesday Sep 09, 2025
Recent Updates in AF Guidelines
Tuesday Sep 09, 2025
Tuesday Sep 09, 2025
Recent Updates in AF Guidelines
Guest: Christopher DeSimone, M.D., Ph.D.
Guest: Abhishek Deshmukh, M.B.B.S.
Host: Anthony H. Kashou, M.D.
There have been several recent publications from major societies (ACC/HRS/EHRA/ESC) regarding atrial fibrillation management updates. These include updates to treatment interventions in patients with AFib such as catheter ablation, medical therapy, heart failure, and timing of intervention.
Topics Discussed:
- What are the new recommendations on catheter ablation?
- What is new regarding the relationship between atrial fibrillation and heart failure?
- Are there new guidelines on Intervention and timing in atrial fibrillation management?
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!
No CME credit offered for this episode.
Podcast episode transcript found here.
